学位：博士研究生

职称/职务：讲师

E-mail：sduzqq@163.com

研究方向：木质纤维素降解转化技术及真菌基因转录调控机制

赵芹芹，女，博士，讲师。2025年6月毕业于山东大学微生物学专业，获得理学博士学位，2025年8月入职永利yl23411集团。在Chemical Engineering Journal、Synthetic and Systems Biotechnology、PLoS Genetics、Journal Of Industrial Microbiology & Biotechnology等期刊发表多篇论文。

主持或参加科研项目（课题）情况:

国家重点研发计划课题，2018YFA0900503，高版本蛋白质生产的丝状真菌底盘细胞构建，2019.7-2024.6，参与。

近年来发表的代表性论文：

1.Zhao Q, Zhang Z, Liu Z, Liang H, Gao L, Zhao J*, Liu G*, Qu Y. A closed-loop strategy for on-site production of saccharolytic enzymes for lignocellulose biorefinery using internal lignocellulosic hydrolysates.Chem Eng J, 2024, 480:148272.

2.Zhao Q, Yang Z, Xiao Z, Zhang Z, Xing Z, Gao L, Zhao J, Qu Y,Liu G*,Structure-guided engineering of transcriptional activator XYR1 for inducer-free production of lignocellulolytic enzymes in Trichoderma reesei. Synt Sys Biotechnol, 2023, 8:732–740.

3.Zhao Q, Gao L, Xu N, Zhang X, Qin Y, Qu Y, Liu G*. An l-fucose-responsive transcription factor cross-regulates the expression of a diverse array of carbohydrate-active enzymes in Trichoderma reesei. PLoS Genet, 2025, 21(8): e1011815.

4.Zhao Q, Liu Q, Wang Q, et al. Disruption of the Trichoderma reeseigul1gene stimulates hyphal branching and reduces broth viscosity in cellulase production. J Ind Microbiol Biotechnol, 2021, 48:kuab012.

5.Xiao Z,Zhao Q, Li W, Gao L, Liu G*. Strain improvement ofTrichoderma harzianumfor enhanced biocontrol capacity: Strategies and prospects. Front Microbiol, 2023, 14: 1146210.

6.Gao L,Liu G,Zhao Q, Xiao Z, Sun W, Hao X, Liu X, Zhang Z, Zhang P*. Customized optimization of lignocellulolytic enzyme cocktails for efficient conversion of pectin-rich biomass residues.Carbohyd Polym, 2022, 297:120025.

7. Xing J, Zhang Z,Zhao Q,Influence of one-step enzymatic modification on the structure, physicochemical, and functional properties of dietary fiber from corn husk rich in (hemi)cellulose. International journal of biological macromolecules vol. 317,Pt 1 (2025): 144683.

8.Jiang S, Wang Y, Liu Q,Zhao Q, Gao L, Song X, Li X, Qu Yi, Liu G. Genetic engineering and raising temperature enhance recombinant protein production with thecdna1promoter inTrichoderma reesei.Bioresour Bioprocess. 2022,9, 113.

授权专利：

1.刘国栋，赵芹芹，高丽伟，李雪芝，曲音波.一种将木质纤维素水解液回用于发酵生产纤维素酶液的方法：ZL 2021 1 1041885.6[P]. 2022-07-22.

2.刘国栋，赵芹芹，肖子扬，高丽伟，曲音波.一种真菌木质纤维素降解酶合成调控蛋白突变体及其应用：ZL 2023 1 0831499.X[P]. 2024-08-09.

3.刘国栋，姜珊珊，赵芹芹，王悦，刘琴，曲音波.一种里氏木霉cbh1基因启动子突变体及其构建方法和应用：ZL 2021 1 1403041.1[P]. 2022-06-14.